Phosphoric Acid

Phosphoric Acid

SCHEMBL23748501

O=C(Nc1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1)c1ccccc1.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O

nearest known ligand 0.72

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADRB1 known ✓ P08588 1/20 0.47
POLB P06746 2/20 0.72
ABL1 P00519 1/20 0.65
RIN1 Q13671 1/20 0.65
P2RY6 Q15077 2/20 0.54
P2RY14 Q15391 2/20 0.54
NT5E P21589 2/20 0.54
DNMT1 P26358 5/20 0.47
DNMT3B Q9UBC3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL264066 0.97 POLB (0.76) POLBABL1RIN1P2RY6P2RY14
SCHEMBL264065 0.97 POLB (0.76) POLBABL1RIN1P2RY6P2RY14
SCHEMBL28795634 0.97 POLB (0.76) POLBABL1RIN1P2RY6P2RY14
SCHEMBL14733368 0.97 POLB (0.76) POLBABL1RIN1P2RY6P2RY14
SCHEMBL6524192 0.93 POLB (0.70) POLBABL1RIN1P2RY6P2RY14
SCHEMBL9706035 0.91 POLB (0.68) POLBABL1RIN1P2RY6P2RY14
SCHEMBL14429249 0.90 POLB (0.72) POLBABL1RIN1P2RY6P2RY14
SCHEMBL14568644 0.90 POLB (0.72) POLBABL1RIN1P2RY6P2RY14
SCHEMBL14568629 0.90 POLB (0.72) POLBABL1RIN1P2RY6P2RY14
SCHEMBL14429239 0.90 POLB (0.72) POLBABL1RIN1P2RY6P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12188013-B2 Catalytic biomolecule activity recording into DNA sequence VILNIUS UNIVERSITY (LT) 2025-01-07 US claimed
US-20210355486-A1 CATALYTIC BIOMOLECULE ACTIVITY RECORDING INTO DNA SEQUENCE UAB BIOMATTER DESIGNS (LT) 2021-11-18 US claimed
EP-3864168-A1 CATALYTIC BIOMOLECULE ACTIVITY RECORDING INTO DNA SEQUENCE Vilnius University (LT) 2021-08-18 EP claimed