Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PHF13 | Q86YI8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23021775 | 0.78 | CD274 (0.60) | ALDH1A1 | |
| SCHEMBL5474202 | 0.77 | ALDH1A1 (0.71) | L3MBTL1MAPTRECQLKMT2ACYP1A2 | |
| SCHEMBL14430740 | 0.76 | MAPT (0.59) | L3MBTL3L3MBTL1MAPTRECQLKMT2A | |
| SCHEMBL17873924 | 0.76 | SMN1; SMN2 (0.76) | L3MBTL3L3MBTL1PHF13NAMPTALDH1A1 | |
| SCHEMBL8919914 | 0.76 | KDM4E (0.48) | ALDH1A1 | |
| SCHEMBL1833770 | 0.76 | POLB (0.62) | L3MBTL3L3MBTL1MAPTRECQLSLC29A1 | |
| SCHEMBL14430744 | 0.76 | MAPT (0.46) | L3MBTL3L3MBTL1PHF13MAPTRECQL | |
| SCHEMBL1384427 | 0.76 | ALDH1A1 (0.72) | L3MBTL3L3MBTL1MAPTRECQLKMT2A | |
| SCHEMBL10245161 | 0.75 | SMN1; SMN2 (0.54) | L3MBTL1NAMPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL13211930 | 0.75 | NPSR1 (0.79) | L3MBTL3L3MBTL1MAPTRECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191358-A1 | Novel piperidine derivative for the treatment of depression | ASTRAZENECA AB (SE) | 2007-08-16 | — | — | US | disclosed |
| US-20070191358-A1 | Novel piperidine derivative for the treatment of depression | ASTRAZENECA AB (SE) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191358-A1 | Novel piperidine derivative for the treatment of depression | GRIN2C, TPH2, HTR5A | L3MBTL3 4276/4885L3MBTL1 4051/4885PHF13 2903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.