Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | HINT1 | P49773 | 6/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14931023 | 1.00 | PNP (0.43) | PNPGSK3ARPS6KA3MAPK14TAAR1 | |
| SCHEMBL3029887 | 0.90 | HINT1 (0.48) | PNPGSK3ARPS6KA3MAPK14TAAR1 | |
| SCHEMBL9962903 | 0.89 | GSK3A (0.40) | GSK3ARPS6KA3MAPK14STING1 | |
| SCHEMBL14536784 | 0.89 | GSK3A (0.40) | GSK3ARPS6KA3MAPK14STING1 | |
| SCHEMBL13747670 | 0.87 | ADORA3 (0.34) | HINT1STING1 | |
| SCHEMBL17410063 | 0.86 | ADORA2B (0.34) | HINT1STING1 | |
| SCHEMBL14930904 | 0.86 | HPGD (0.45) | PNPHINT1HPGDSTING1 | |
| SCHEMBL18573929 | 0.85 | PNP (0.47) | PNPGSK3ARPS6KA3MAPK14TAAR1 | |
| SCHEMBL14931022 | 0.84 | HINT1 (0.43) | HINT1HPGDSTING1 | |
| SCHEMBL9962904 | 0.83 | TYMP (0.37) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501848-B1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | SANTARIS PHARMA AS (DK) | 2007-08-08 | — | — | EP | disclosed |