SCHEMBL14431107

SCHEMBL14431107

C=CCC(=O)Nc1cccc(/N=N\S(=O)(=O)O)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.41
MAOA P21397 3/20 0.41
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 4/20 0.36
POLB P06746 1/20 0.35
NR4A1 P22736 1/20 0.35
RAB9A P51151 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
P2RY6 Q15077 1/20 0.34
LMNA P02545 1/20 0.34
NQO2 P16083 1/20 0.34
GAA P10253 2/20 0.34
TGM2 P21980 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14431281 0.84 MAPT (0.42) MAOBMEN1KMT2AMAPTPOLB
SCHEMBL14431101 0.83 TGM2 (0.52) LMNATGM2
SCHEMBL14431058 0.80 MAPT (0.36) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL15552645 0.79 POLB (0.51) MAOBMAOAMEN1KMT2AMAPT
SCHEMBL14431060 0.76 TDP1 (0.55) CA1CA2MAPTPOLBALDH1A1
SCHEMBL8078447 0.76 TDP1 (0.55) CA1CA2MAPTPOLBALDH1A1
SCHEMBL11133440 0.73 NLRP3 (0.55) MEN1KMT2AMAPTRAB9AALDH1A1
SCHEMBL31303722 0.71 NLRP3 (0.56) MAOBMAOACA1CA2MEN1
SCHEMBL2576588 0.70 MAOB (0.61) MAOBMEN1KMT2AMAPTALDH1A1
SCHEMBL14431279 0.70 TDP1 (0.39) CA1CA2POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1541346-B1 Process for making planographic printing plates, and printing process KONICA MINOLTA MED & GRAPHIC (JP) 2007-08-22 EP disclosed
US-7163779-B2 Planographic printing plate material process, planographic printing plate and printing process KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-16 US disclosed
US-7163779-B2 Planographic printing plate material process, planographic printing plate and printing process KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-16 US disclosed