SCHEMBL8078447

SCHEMBL8078447

C=C(C)C(=O)Nc1cccc(N=NS(=O)(=O)O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.55
MAPT P10636 2/20 0.42
RXFP1 Q9HBX9 1/20 0.39
POLB P06746 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
GPR35 Q9HC97 1/20 0.38
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 1/20 0.38
EGFR P00533 1/20 0.38
ERBB2 P04626 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
JAK3 P52333 4/20 0.36
BAZ1A Q9NRL2 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14431060 1.00 TDP1 (0.55) TDP1MAPTRXFP1POLBL3MBTL1
SCHEMBL14690307 0.87 TDP1 (0.66) TDP1MAPTRXFP1POLBL3MBTL1
SCHEMBL14431101 0.80 TGM2 (0.52) EGFRLMNAJAK3
SCHEMBL1098272 0.77 TDP1 (0.79) TDP1RXFP1POLBL3MBTL1RECQL
SCHEMBL7597973 0.77 TDP1 (0.64) TDP1MAPTRXFP1POLBL3MBTL1
SCHEMBL14431058 0.76 MAPT (0.36) TDP1MAPTPOLBRECQLBLM
SCHEMBL14431107 0.76 MAOB (0.41) MAPTPOLBALDH1A1LMNACA1
SCHEMBL1811660 0.76 TDP1 (0.62) TDP1MAPTRXFP1POLBGPR35
SCHEMBL14431109 0.75 ALDH1A1 (0.35) TDP1RXFP1POLBL3MBTL1ALDH1A1
SCHEMBL14431108 0.74 CA1 (0.39) TDP1MAPTPOLBL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0771645-B1 On-press development of a lithographic printing plate having an aryldiazosulfonate resin in a photosensitive layer AGFA GEVAERT NV (BE) 2000-08-23 EP disclosed
US-5786128-A On-press development of a lithographic printing plate having an aryldiazosulfonate resin in a photosensitive layer AFGA-GEVAERT, N.V. (BE) 1998-07-28 US disclosed
EP-0771645-A1 On-press development of a lithographic printing plate having an aryldiazosulfonate resin in a photosensitive layer AGFA-GEVAERT N.V. (BE) 1997-05-07 EP disclosed