SCHEMBL1443129

SCHEMBL1443129

C[C@](CCCCN)(C(=O)O)N(C(=O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 4/20 0.38
ARG2 P78540 4/20 0.38
ODC1 P11926 2/20 0.36
CYP2D6 P10635 1/20 0.35
NFKB1 P19838 1/20 0.35
BLM P54132 3/20 0.34
LMNA P02545 3/20 0.34
NPSR1 Q6W5P4 2/20 0.34
THRB P10828 2/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PLG P00747 1/20 0.34
ALOX15 P16050 1/20 0.34
SLC6A2 P23975 1/20 0.34
RECQL P46063 1/20 0.34
SLC6A3 Q01959 1/20 0.34
FDPS P14324 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL181191 0.82 ODC1 (0.37) ARG1ARG2ODC1CYP2D6NFKB1
SCHEMBL30156940 0.82 ODC1 (0.37) ARG1ARG2ODC1CYP2D6NFKB1
SCHEMBL157457 0.82 ODC1 (0.37) ARG1ARG2ODC1CYP2D6NFKB1
SCHEMBL27989280 0.82 ODC1 (0.37) ARG1ARG2ODC1CYP2D6NFKB1
Water SCHEMBL21225404 0.81 ODC1 (0.36) ARG1ARG2ODC1CYP2D6NFKB1
Hydrochloric Acid SCHEMBL21225312 0.81 BLM (0.39) ARG1ARG2ODC1CYP2D6NFKB1
SCHEMBL180302 0.76 ODC1 (0.42) ARG1ARG2ODC1CYP2D6NFKB1
SCHEMBL180301 0.76 ODC1 (0.42) ARG1ARG2ODC1CYP2D6NFKB1
SCHEMBL5716372 0.74 GGT1 (0.34) ARG1ARG2THRBKMT2AMEN1
SCHEMBL9595205 0.74 ODC1 (0.41) ARG1ARG2ODC1CYP2D6NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050123932-A1 Nucleic acid-chelating agent conjugates KIRKEGAARD & PERRY LABORATORIES, INC. 2005-06-09 US claimed
US-RE50618-E1 Anionic-core composition for delivery of therapeutic agents, and methods of making and using the same PHARMAIN CORPORATION (US) 2025-10-07 US disclosed
US-20200254100-A1 ANIONIC-CORE COMPOSITION FOR DELIVERY OF THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USING THE SAME PHARMAIN CORPORATION (US) 2020-08-13 US disclosed
US-10624966-B2 Anionic-core composition for delivery of therapeutic agents, and methods of making and using the same PHARMAIN CORPORATION (US) 2020-04-21 US disclosed
EP-2475358-B1 ANIONIC-CORE COMPOSITION FOR DELIVERY OF THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USING THE SAME PHARMAIN CORP (US) 2019-06-05 EP disclosed
US-20180280516-A1 ANIONIC-CORE COMPOSITION FOR DELIVERY OF THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USING THE SAME PHARMAIN CORPORATION (US) 2018-10-04 US disclosed
US-10010613-B2 Anionic-core composition for delivery of therapeutic agents, and methods of making and using the same PHARMAIN CORPORATION (US) 2018-07-03 US disclosed
US-20120190097-A1 ANIONIC-CORE COMPOSITION FOR DELIVERY OF THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USING THE SAME PHARMAIN CORPORATION 2012-07-26 US disclosed
EP-2475358-A1 ANIONIC-CORE COMPOSITION FOR DELIVERY OF THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USING THE SAME Pharmain Corporation (US) 2012-07-18 EP disclosed
EP-1461619-B1 IMPROVED STRUCTURED-FUNCTIONAL BONDING MATRICES FOR BIOMOLECULES FRAUNHOFER GES FORSCHUNG (DE) 2011-04-27 EP disclosed
WO-2011031771-A1 ANIONIC-CORE COMPOSITION FOR DELIVERY OF THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USING THE SAME PHARMAIN CORPORATION (US) 2011-03-17 WO disclosed
WO-2011031284-A1 POLYMERIC CARRIER COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS, METHODS OF MAKING AND USING THE SAME PHARMAIN CORPORATION (US) 2011-03-17 WO disclosed
US-20100069293-A1 POLYMERIC CARRIER COMPOSITIONS FOR DELIVERY OF ACTIVE AGENTS, METHODS OF MAKING AND USING THE SAME PHARMAIN CORPORATION (US) 2010-03-18 US disclosed
US-7368295-B2 Nanoparticles comprising biologically active TNF which is immobilized on the same FRAUNHOFER-GESELLSCHAFT ZUR FODERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2008-05-06 US disclosed
US-7202472-B2 Mass spectrometric analysis using nanoparticles FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2007-04-10 US disclosed
US-20050123932-A1 Nucleic acid-chelating agent conjugates KIRKEGAARD & PERRY LABORATORIES, INC. 2005-06-09 US disclosed
US-20050048570-A1 Structured-functional bonding matrices for biomolecules FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN 2005-03-03 US disclosed
US-20050037516-A1 Using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) to diagnose infection, cell proliferative and spongiform encephalopathic disorders FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E. V. (DE) 2005-02-17 US disclosed
US-20040265392-A1 Nanoparticles comprising biologically active tnf which is immobilized on the same FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2004-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050123932-A1 Nucleic acid-chelating agent conjugates RNGTT, SAMHD1, DNTT ARG1 1875/4885ARG2 2699/4885ODC1 1088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.