Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | EBP | Q15125 | 2/20 | 0.54 |
| ▸ | CCR3 | P51677 | 2/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 4/20 | 0.44 |
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14431859 | 0.96 | CCR3 (0.54) | RAB9ANPSR1CHRM4CHRM5CHRM3 | |
| SCHEMBL5240018 | 0.93 | RAB9A (0.52) | RAB9ANPSR1CHRM4CHRM5CHRM3 | |
| SCHEMBL14431854 | 0.92 | SIGMAR1 (0.51) | RAB9ANPSR1CHRM4CHRM5CHRM3 | |
| SCHEMBL5750440 | 0.90 | CCR3 (0.52) | RAB9ANPSR1CHRM4CHRM5CHRM3 | |
| SCHEMBL5754473 | 0.90 | SIGMAR1 (0.49) | RAB9ANPSR1CHRM4CHRM5CHRM3 | |
| SCHEMBL5239804 | 0.89 | KCNA3 (0.60) | RAB9ANPSR1CHRM4CHRM3SIGMAR1 | |
| SCHEMBL5237846 | 0.89 | SIGMAR1 (0.60) | RAB9ANPSR1CHRM4CHRM5CHRM3 | |
| SCHEMBL5239794 | 0.89 | SIGMAR1 (0.60) | SIGMAR1EBPCCR3KCNA3 | |
| SCHEMBL5235995 | 0.88 | CHRM4 (0.54) | RAB9ANPSR1CHRM4CHRM5CHRM3 | |
| SCHEMBL14431853 | 0.88 | RAB9A (0.57) | RAB9ANPSR1CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1818326-A1 | Nitrogen-containing heterocyclic compounds and pharmaceutical composition containing the compounds | Eisai R&D Management Co., Ltd. (JP) | 2007-08-15 | — | — | EP | disclosed |