SCHEMBL14432144

SCHEMBL14432144

Cc1cc(Cl)c(C2=C(OC(=O)C(C)(C)C)C(C)(C)NC2=O)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14609666 0.83 GSK3B (0.37) L3MBTL1MAPT
SCHEMBL812085 0.77 PGR (0.38) L3MBTL1
SCHEMBL12658143 0.76 MAP3K14 (0.37) L3MBTL1MAPT
SCHEMBL14432147 0.75 ACACB (0.37)
SCHEMBL10230209 0.75 CNR2 (0.32) L3MBTL1MAPT
SCHEMBL9883897 0.73 L3MBTL1 (0.32) L3MBTL1
SCHEMBL13527210 0.71 L3MBTL1 (0.31) L3MBTL1
SCHEMBL13673311 0.71 TGM2 (0.40) L3MBTL1
SCHEMBL13097092 0.71 NPC1 (0.30)
SCHEMBL10211989 0.69 MCHR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7256158-B2 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 2007-08-14 US disclosed
US-7256158-B2 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 2007-08-14 US disclosed