Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14431654 | 0.82 | SCN3A (0.38) | SCN3AMAOAMAOBRAB9AALDH1A1 | |
| SCHEMBL9955740 | 0.78 | DGAT1 (0.46) | DGAT1BRD4BRD2BRD3BRDT | |
| SCHEMBL4453247 | 0.78 | SCN3A (0.57) | SCN3AMAOBMEN1ALDH1A1KMT2A | |
| SCHEMBL12473692 | 0.76 | DGAT1 (0.50) | DGAT1BRD4BRD2BRD3BRDT | |
| SCHEMBL6884493 | 0.76 | MTNR1B (0.57) | — | |
| SCHEMBL18497253 | 0.73 | — | — | |
| SCHEMBL14431556 | 0.73 | TAAR1 (0.54) | CA12CA1CA2NPC1RAB9A | |
| SCHEMBL27894000 | 0.72 | DGAT1 (0.46) | DGAT1USP28BRD4BRD2BRD3 | |
| SCHEMBL5041752 | 0.71 | TAAR1 (0.50) | DGAT1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7868984 | 0.71 | SCN3A (0.50) | SCN3AMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490371-B1 | THIOPHENE-BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | BRISTOL MYERS SQUIBB CO (US) | 2007-08-15 | — | — | EP | disclosed |