Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 4/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18497253 | 0.85 | — | — | |
| SCHEMBL1477663 | 0.84 | SETDB1 (0.56) | MTNR1BMTNR1A | |
| SCHEMBL17689405 | 0.84 | MTNR1A (0.59) | MTNR1BMTNR1ANOTUM | |
| SCHEMBL5037850 | 0.79 | MTNR1A (0.45) | MTNR1BMTNR1ANOTUM | |
| SCHEMBL6555821 | 0.79 | MTNR1B (0.64) | MTNR1BMTNR1A | |
| SCHEMBL31039288 | 0.78 | MTNR1B (0.53) | MTNR1BMTNR1ANOTUM | |
| SCHEMBL1010476 | 0.77 | MTNR1A (0.61) | MTNR1BMTNR1A | |
| SCHEMBL14432149 | 0.76 | DGAT1 (0.41) | — | |
| SCHEMBL5041138 | 0.75 | EGFR (0.46) | — | |
| SCHEMBL27860277 | 0.75 | ALDH1A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004075846-A2 | PYRAZOLOPURINE-BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-10 | — | — | WO | disclosed |