SCHEMBL14432173

SCHEMBL14432173

CC1=C(c2cc(Cl)c(Cl)cc2Cl)C(=O)NC1(C)C1CC1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.34
CES1 P23141 1/20 0.33
SLC6A2 P23975 5/20 0.32
SLC6A4 P31645 5/20 0.32
SLC6A3 Q01959 5/20 0.32
ACACB O00763 5/20 0.32
ACACA Q13085 5/20 0.32
MAPK1 P28482 1/20 0.31
AHR P35869 1/20 0.31
NR3C1 P04150 1/20 0.30
PGR P06401 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14432174 0.84 ACACB (0.35) L3MBTL1CES1ACACBACACA
SCHEMBL12401985 0.69 ALDH1A1 (0.33) L3MBTL1
SCHEMBL13960141 0.69 GSK3B (0.36) L3MBTL1ACACBACACA
SCHEMBL812106 0.67 TDP2 (0.46) ACACBACACA
SCHEMBL13527261 0.67
SCHEMBL2363264 0.66 ACACB (0.62) L3MBTL1ACACBACACAPGR
SCHEMBL16153993 0.65 NR1H3 (0.46) L3MBTL1MAPK1
SCHEMBL5492009 0.64 DDB1 (0.32) L3MBTL1
SCHEMBL4439032 0.64 ACACB (0.35) ACACBACACA
SCHEMBL14432147 0.62 ACACB (0.37) CES1ACACBACACANR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7256158-B2 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 2007-08-14 US disclosed