SCHEMBL5492009

SCHEMBL5492009

CC1(C2CC2)NC(=O)C(c2cc(Cl)c(Cl)cc2Cl)C1=O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.32
CRBN Q96SW2 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7780304 0.79 TP53 (0.40) L3MBTL1
SCHEMBL6314284 0.75 L3MBTL1 (0.34) L3MBTL1
SCHEMBL7781016 0.74 DDB1 (0.36) DDB1CRBNL3MBTL1
SCHEMBL2969282 0.73 MTOR (0.34)
SCHEMBL5929376 0.73 L3MBTL1 (0.31) L3MBTL1
SCHEMBL7780291 0.72 CRBN (0.33) DDB1CRBNL3MBTL1
SCHEMBL1813846 0.71 ACHE (0.31)
SCHEMBL14444878 0.71 DDB1 (0.35) DDB1CRBN
SCHEMBL4433818 0.70 CA2 (0.49) DDB1CRBN
SCHEMBL7142077 0.70 GRIN2D (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7256158-B2 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 2007-08-14 US disclosed
US-6933261-B2 2,4,5-Trisubstituted phenylketoenols BAYER AKTIENGESELLSCHAFT (DE) 2005-08-23 US disclosed
US-20050038021-A1 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 2005-02-17 US disclosed
US-6511942-B1 Animal husbandry, veterinary medicine BAYER AKTIENGESELLSCHAFT (DE) 2003-01-28 US disclosed
EP-0837847-B1 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES BAYER AG (DE) 2002-09-18 EP disclosed
EP-0837847-A1 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES BAYER AG (DE) 1998-04-29 EP disclosed
WO-1997001535-A1 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-01-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038021-A1 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides DDT, CYP4X1, PDHX DDB1 1889/4885CRBN 3434/4885L3MBTL1 1645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.