Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 10/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4912744 | 0.91 | MAPK14 (0.38) | MAPK14OXTRGHSRGPBAR1 | |
| SCHEMBL14432384 | 0.90 | CTSK (0.34) | MAPK14OXTRGHSRGPBAR1 | |
| SCHEMBL14258886 | 0.90 | KDR (0.39) | MAPK14OXTRGHSRGPBAR1 | |
| SCHEMBL4909403 | 0.90 | MAPK14 (0.36) | MAPK14OXTRGHSRGPBAR1 | |
| SCHEMBL4933816 | 0.89 | MAPK14 (0.37) | MAPK14OXTRGHSRGPBAR1 | |
| SCHEMBL4933826 | 0.89 | MAPK14 (0.37) | MAPK14OXTRGHSRGPBAR1 | |
| SCHEMBL4910784 | 0.89 | HRH3 (0.39) | MAPK14OXTRGHSRGPBAR1MAP3K11 | |
| SCHEMBL14258848 | 0.89 | OXTR (0.36) | MAPK14OXTRGHSRGPBAR1 | |
| SCHEMBL4908666 | 0.88 | OXTR (0.35) | MAPK14OXTRGHSRGPBAR1 | |
| SCHEMBL4914320 | 0.88 | ALDH1A1 (0.37) | MAPK14OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1820799-A1 | 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION | Wakamoto Pharmaceutical Co., Ltd. (JP) | 2007-08-22 | — | — | EP | disclosed |