Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.58 |
| ▸ | CALML3 | P27482 | 7/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SDHA | P31040 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1393183 | 0.88 | MAOA (0.53) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393880 | 0.88 | MAOA (0.53) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393882 | 0.88 | MAOA (0.53) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL12075302 | 0.87 | MAOA (0.52) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1394259 | 0.86 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL14026448 | 0.86 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL7938091 | 0.85 | MAOA (0.65) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL6023183 | 0.85 | MAOA (0.56) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1394850 | 0.85 | MAOA (0.64) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3179763 | 0.85 | MAOA (0.56) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197541-A1 | Biaryl heterocyclic amines,amides, and sulfur-containing compounds and methods of making and using the same | RIB-X PHARMACEUTICALS, INC. | 2007-08-23 | — | — | US | disclosed |
| US-20070197541-A1 | Biaryl heterocyclic amines,amides, and sulfur-containing compounds and methods of making and using the same | RIB-X PHARMACEUTICALS, INC. | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197541-A1 | Biaryl heterocyclic amines,amides, and sulfur-containing compounds and methods of making and using the same | SQOR, AADAC, TST | MAOA 605/4885CALML3 2657/4885MAOB 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.