Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.67 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.63 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844957 | 0.82 | CNR1 (0.80) | CNR1TAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL18317283 | 0.80 | CNR1 (0.76) | CNR1TAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL22834166 | 0.80 | CNR1 (1.00) | CNR1TAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL12994638 | 0.80 | CNR1 (0.76) | CNR1TAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL29615054 | 0.80 | CNR1 (1.00) | CNR1TAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL11617438 | 0.77 | CA12 (0.71) | CNR1TAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL702289 | 0.77 | TAS1R3 (1.00) | CNR1TAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL706185 | 0.76 | CA12 (0.70) | CNR1TAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL11613062 | 0.76 | LMNA (0.63) | CNR1TAS1R3TAS1R1RAB9ACA1 | |
| SCHEMBL3716649 | 0.74 | L3MBTL1 (0.64) | CNR1TAS1R3TAS1R1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076055-A9 | COMPOSITIONS AND METHODS COMPRISING PROTEINASE ACTIVATED RECEPTOR ANTAGONISTS | ENTREMED INC (US) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007076055-A2 | COMPOSITIONS AND METHODS COMPRISING PROTEINASE ACTIVATED RECEPTOR ANTAGONISTS | ENTREMED, INC. (US) | 2007-07-05 | — | — | WO | disclosed |