Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | CRHBP | P24387 | 1/20 | 0.65 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | QPCT | Q16769 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692030 | 0.86 | ALDH1A1 (0.68) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL7692027 | 0.82 | ALDH1A1 (0.69) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL6814650 | 0.78 | ALDH1A1 (0.61) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL14433882 | 0.75 | ALDH1A1 (0.86) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL28542942 | 0.75 | ALDH1A1 (0.86) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL12884376 | 0.74 | LMNA (0.72) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL3631999 | 0.74 | QPCT (0.84) | LMNAALDH1A1MAPTQPCT | |
| SCHEMBL8979285 | 0.74 | LMNA (0.70) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL22834237 | 0.74 | CNR1 (1.00) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL29614996 | 0.74 | CNR1 (1.00) | KMT2AMEN1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076055-A9 | COMPOSITIONS AND METHODS COMPRISING PROTEINASE ACTIVATED RECEPTOR ANTAGONISTS | ENTREMED INC (US) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007076055-A2 | COMPOSITIONS AND METHODS COMPRISING PROTEINASE ACTIVATED RECEPTOR ANTAGONISTS | ENTREMED, INC. (US) | 2007-07-05 | — | — | WO | disclosed |