SCHEMBL8979285

SCHEMBL8979285

CCNC(=S)Nc1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.70
SMN1; SMN2 Q16637 6/20 0.70
KMT2A Q03164 5/20 0.64
MEN1 O00255 4/20 0.64
POLB P06746 1/20 0.63
MAPT P10636 4/20 0.60
GAA P10253 3/20 0.60
NPSR1 Q6W5P4 1/20 0.60
CYP19A1 P11511 1/20 0.58
KDM4E B2RXH2 1/20 0.58
PKM P14618 1/20 0.58
CRHBP P24387 1/20 0.58
CRHR2 Q13324 1/20 0.58
ALDH1A1 P00352 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8956298 0.84 LMNA (0.74) LMNASMN1; SMN2KMT2AMEN1POLB
SCHEMBL13761437 0.82 ALDH1A1 (0.65) LMNASMN1; SMN2KMT2APOLBMAPT
SCHEMBL5455321 0.82 SMN1; SMN2 (0.66) LMNASMN1; SMN2KMT2AMEN1POLB
SCHEMBL8956455 0.81 MAPT (0.75) LMNASMN1; SMN2KMT2AMEN1MAPT
SCHEMBL5445907 0.81 MAPT (0.75) LMNASMN1; SMN2KMT2AMEN1MAPT
SCHEMBL14386215 0.81 SMN1; SMN2 (0.68) LMNASMN1; SMN2KMT2APOLBMAPT
SCHEMBL11072927 0.81 CYP1A2 (0.74) LMNASMN1; SMN2KMT2AMEN1POLB
SCHEMBL8611488 0.81 ALDH1A1 (0.81) LMNASMN1; SMN2KMT2APOLBMAPT
SCHEMBL6096417 0.81 GAA (0.62) LMNASMN1; SMN2KMT2AMEN1POLB
SCHEMBL13735975 0.80 LMNA (0.69) LMNASMN1; SMN2KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5236633-A Blend of transparent polymer, thiourea and copper compounds JUJO PAPER CO., LTD. (JP) 1993-08-17 US claimed
US-4264710-A AN ETHYLENICALLY UNSATURATED COMPOUND, AND A PHOTOPOLYMERIZATION INIATOR FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US claimed
CN-115368282-A Method for synthesizing 1, 3-disubstituted thiourea in aqueous phase 吉安宏达秋科技有限公司 2022-11-22 CN disclosed
CN-1315936-C Flame-resistant vinyl chloride based resin composition and formed product therefrom MITSUBISHI PLASTICS INC (JP) 2007-05-16 CN disclosed
CN-1708550-A Flame-resistant vinyl chloride based resin composition and formed product therefrom MITSUBISHI PLASTICS INC (JP) 2005-12-14 CN disclosed
US-5514740-A SHEET OR FILM HAVING CUPRIC SULFIDE DISPERSED THEREIN DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1996-05-07 US disclosed
US-5393443-A Hard-coating, heat-absorbing composition and heat-shielding substance JUJO PAPER CO., LTD. (JP) 1995-02-28 US disclosed
US-4461821-A Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound FUJI PHOTO FILM CO., LTD. (JP) 1984-07-24 US disclosed