Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435969 | 0.90 | SCN9A (0.47) | SCN9ANR1I2PRKCAMMP12CYP3A4 | |
| SCHEMBL804071 | 0.87 | PRKCA (0.53) | SCN9ANR1I2PRKCAMMP12CYP3A4 | |
| SCHEMBL14435970 | 0.85 | SCN9A (0.43) | SCN9ANR1I2PRKCAMMP12CYP3A4 | |
| SCHEMBL3571775 | 0.82 | PRKCA (0.52) | SCN9ANR1I2PRKCAMMP12CYP3A4 | |
| SCHEMBL14435398 | 0.82 | SCN9A (0.48) | SCN9ANR1I2PRKCAMMP12CYP3A4 | |
| SCHEMBL3569189 | 0.81 | SCN9A (0.45) | SCN9ANR1I2PRKCAMMP12CYP3A4 | |
| SCHEMBL14435944 | 0.78 | SCN9A (0.43) | SCN9ANR1I2PRKCAMMP12KCNH2 | |
| SCHEMBL14435357 | 0.76 | SCN9A (0.54) | SCN9ANR1I2PRKCAMMP12CYP3A4 | |
| SCHEMBL12427557 | 0.76 | PRKCA (0.51) | SCN9ANR1I2PRKCAMMP12CYP3A4 | |
| SCHEMBL10283745 | 0.76 | PRKCA (0.46) | SCN9ANR1I2PRKCAMMP12CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092000-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |