⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17520317 | 0.78 | — | — | |
| SCHEMBL18735795 | 0.78 | — | — | |
| SCHEMBL9975623 | 0.78 | TSHR (0.33) | — | |
| SCHEMBL13949324 | 0.74 | — | — | |
| SCHEMBL19278313 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL13595286 | 0.70 | FDPS (0.37) | — | |
| SCHEMBL6861480 | 0.69 | TSHR (0.33) | — | |
| SCHEMBL17322974 | 0.68 | — | — | |
| SCHEMBL14818215 | 0.68 | — | — | |
| SCHEMBL12274357 | 0.67 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603941-B2 | Method of preparing dendritic drugs | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES | 2017-03-28 | — | — | US | disclosed |
| US-20160206746-A1 | METHOD OF PREPARING DENDRITIC DRUGS | CHAI MINGHUI (CN) | 2016-07-21 | — | — | US | disclosed |
| US-20070190151-A1 | Method of preparing dendritic drugs | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES | 2007-08-16 | — | — | US | disclosed |
| WO-2007087256-A2 | METHOD OF PREPARING DENDRITIC DRUGS | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES (US) | 2007-08-02 | — | — | WO | disclosed |