Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17193315 | 0.93 | TSHR (0.33) | TSHRALDH1A1LMNATDP1 | |
| SCHEMBL12042643 | 0.85 | ALDH1A1 (0.44) | TSHRALDH1A1LMNATDP1 | |
| SCHEMBL9679036 | 0.84 | — | — | |
| SCHEMBL14827728 | 0.83 | — | — | |
| SCHEMBL18231991 | 0.81 | LMNA (0.41) | TSHRALDH1A1LMNA | |
| SCHEMBL18231992 | 0.81 | LMNA (0.41) | TSHRALDH1A1LMNA | |
| SCHEMBL1658193 | 0.81 | LMNA (0.41) | TSHRALDH1A1LMNA | |
| SCHEMBL12997564 | 0.79 | — | — | |
| SCHEMBL26710909 | 0.79 | TSHR (0.32) | TSHRALDH1A1LMNATDP1 | |
| SCHEMBL17718585 | 0.79 | ALDH1A1 (0.39) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686331-B2 | PRINCIPAL SOLVENTS, ESPECIALLY MONO AND DIOL PRINCIPAL SOLVENTS, HAVING A SPECIFIED CLOGP VALUE, SPECIFIED TYPES OF SOFTENERS SUCH AS VARISOFT?, WATER AND OPTIONAL ADDITIVES; PREMIX | THE PROCTER & GAMBLE COMPANY | 2004-02-03 | — | — | US | claimed |
| CN-1110541-C | Concentrated water-dispersible stable fiber softener compositions | PROCTER & GAMBLE (US) | 2003-06-04 | — | — | CN | claimed |
| CN-1219953-A | Fabric softening compound/composition | PROCTER & GAMBLE (US) | 1999-06-16 | — | — | CN | claimed |
| CN-1196081-A | Concentrated, water dispersible, stable, fabric softening compositions | PROCTER & GAMBLE (US) | 1998-10-14 | — | — | CN | claimed |
| CN-1195369-A | Concentrated and stable fabric softening compositions | PROCTER & GAMBLE (US) | 1998-10-07 | — | — | CN | claimed |
| US-11773065-B2 | Heterocyclic g-protein-coupled receptor 52 (GPR52) agonists | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-10-03 | — | — | US | disclosed |
| US-11639347-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-05-02 | — | — | US | disclosed |
| US-10036754-B2 | Water soluble fluorescent or colored dyes and methods for their use | SONY CORPORATION (JP) | 2018-07-31 | — | — | US | disclosed |
| US-10022352-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-07-17 | — | — | US | disclosed |
| US-20180162842-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED | 2018-06-14 | — | — | US | disclosed |
| US-9974781-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-05-22 | — | — | US | disclosed |
| US-20180100861-A1 | WATER SOLUBLE FLUORESCENT OR COLORED DYES AND METHODS FOR THEIR USE | SONY CORPORATION (JP) | 2018-04-12 | — | — | US | disclosed |
| US-20100228015-A1 | PRODRUG DERIVATIVES OF ACIDS USING ALCOHOLS WITH HOMOTOPIC HYDROXY GROUPS AND METHODS FOR THEIR PREPARATION AND USE | DELONG MITCHELL A | 2010-09-09 | — | — | US | disclosed |
| US-20100228015-A1 | PRODRUG DERIVATIVES OF ACIDS USING ALCOHOLS WITH HOMOTOPIC HYDROXY GROUPS AND METHODS FOR THEIR PREPARATION AND USE | DELONG MITCHELL A | 2010-09-09 | — | — | US | disclosed |
| US-20070254920-A1 | Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use | AERIE PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | US | disclosed |
| US-20070254920-A1 | Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use | AERIE PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | US | disclosed |
| CN-1219953-A | Fabric softening compound/composition | PROCTER & GAMBLE (US) | 1999-06-16 | — | — | CN | disclosed |
| CN-1195369-A | Concentrated and stable fabric softening compositions | PROCTER & GAMBLE (US) | 1998-10-07 | — | — | CN | disclosed |
| EP-0294228-B1 | NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-08-26 | — | — | EP | disclosed |
| EP-0294228-A2 | Novel heterocyclic pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254920-A1 | Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use | HCAR1, HCAR2, PAICS | TSHR 2474/4885ALDH1A1 102/4885LMNA 3188/4885 |
| US-11639347-B2 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | TSHR 2748/4885ALDH1A1 1961/4885LMNA 3455/4885 |
| US-20180162842-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | TSHR 2748/4885ALDH1A1 1961/4885LMNA 3455/4885 |
| US-10022352-B2 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | TSHR 2748/4885ALDH1A1 1961/4885LMNA 3455/4885 |
| US-20100228015-A1 | PRODRUG DERIVATIVES OF ACIDS USING ALCOHOLS WITH HOMOTOPIC HYDROXY GROUPS AND METHODS FOR THEIR PREPARATION AND USE | HCAR1, HCAR2, PAICS | TSHR 2474/4885ALDH1A1 102/4885LMNA 3188/4885 |
| US-20180100861-A1 | WATER SOLUBLE FLUORESCENT OR COLORED DYES AND METHODS FOR THEIR USE | IK, B2M, TTBK2 | TSHR 329/4885ALDH1A1 1716/4885LMNA 101/4885 |
| US-10036754-B2 | Water soluble fluorescent or colored dyes and methods for their use | IK, B2M, TTBK2 | TSHR 329/4885ALDH1A1 1716/4885LMNA 101/4885 |
| US-11773065-B2 | Heterocyclic g-protein-coupled receptor 52 (GPR52) agonists | GPR52, GPR68, GPR65 | TSHR 552/4885ALDH1A1 2733/4885LMNA 4441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.