Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | UGCG | Q16739 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CALCA | P06881 | 1/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435581 | 0.90 | UGCG (0.42) | ADAM17ADAMTS5CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14435971 | 0.88 | HRH2 (0.48) | HRH2HRH1CYP51A1CYP3A4UGCG | |
| SCHEMBL14435974 | 0.87 | AKT1 (0.46) | HRH2HRH1ADAM17ADAMTS5 | |
| SCHEMBL14436428 | 0.86 | ADAM17 (0.42) | ADAM17ADAMTS5LTA4HHTR2ACYP1A2 | |
| SCHEMBL14435994 | 0.84 | CCR1 (0.42) | CYP51A1ADAM17ADAMTS5CYP3A4UGCG | |
| SCHEMBL14436001 | 0.84 | CCR1 (0.42) | CYP51A1ADAM17ADAMTS5CYP3A4UGCG | |
| SCHEMBL14436005 | 0.84 | CCR1 (0.42) | CYP51A1ADAM17ADAMTS5CYP3A4UGCG | |
| SCHEMBL14435607 | 0.84 | CCR1 (0.42) | CYP51A1ADAM17ADAMTS5CYP3A4UGCG | |
| SCHEMBL14431353 | 0.83 | HRH2 (0.52) | HRH2HRH1CYP51A1CYP3A4UGCG | |
| SCHEMBL14435629 | 0.83 | HRH2 (0.46) | HRH2HRH1CYP51A1CALCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096186-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-08-30 | — | — | WO | disclosed |