Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MC4R | P32245 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | PYGM | P11217 | 1/20 | 0.40 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 4/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435277 | 0.83 | AKT1 (0.46) | MC4RMC3R | |
| SCHEMBL14435276 | 0.83 | AKT1 (0.46) | MC4RMC3R | |
| SCHEMBL14431450 | 0.83 | HRH2 (0.46) | PABPC1KMT2AMC4RMAPK1PYGL | |
| SCHEMBL14435628 | 0.81 | KMT2A (0.46) | PABPC1KMT2AMC4RMAPK1CYP51A1 | |
| SCHEMBL12713231 | 0.81 | GPR119 (0.49) | KMT2A | |
| SCHEMBL12713236 | 0.79 | CALCA (0.44) | MC4RCCR1MC3R | |
| SCHEMBL12713332 | 0.77 | CALCA (0.43) | MC4RCCR1MC3R | |
| SCHEMBL12713335 | 0.77 | CALCA (0.43) | MC4RCCR1MC3R | |
| SCHEMBL4699544 | 0.77 | KMT2A (0.53) | PABPC1KMT2AMC4RMAPK1CCR1 | |
| SCHEMBL14435256 | 0.76 | AKT1 (0.44) | MC4RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096186-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-08-30 | — | — | WO | disclosed |