Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MC4R | P32245 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 5/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435997 | 0.88 | CCR1 (0.43) | MC4RCCR1CYP51A1ALDH1A1CYP3A4 | |
| SCHEMBL14436003 | 0.88 | CCR1 (0.43) | MC4RCCR1CYP51A1ALDH1A1CYP3A4 | |
| SCHEMBL12713182 | 0.88 | CALCA (0.46) | MC4RCCR1CYP51A1ALDH1A1CYP3A4 | |
| SCHEMBL14435972 | 0.84 | KMT2A (0.47) | KMT2AMC4RMAPK1CCR1PABPC1 | |
| SCHEMBL14436006 | 0.83 | ADAM17 (0.43) | KMT2ACCR1CYP51A1ALDH1A1 | |
| SCHEMBL14436008 | 0.83 | ADAM17 (0.43) | KMT2ACCR1CYP51A1ALDH1A1 | |
| SCHEMBL14435596 | 0.83 | AKT1 (0.43) | — | |
| SCHEMBL12713175 | 0.83 | TP53 (0.45) | KMT2AALDH1A1LMNA | |
| SCHEMBL14435600 | 0.81 | PABPC1 (0.46) | KMT2AMC4RMAPK1CCR1PABPC1 | |
| SCHEMBL14435971 | 0.81 | HRH2 (0.48) | KMT2AMC4RMAPK1PABPC1CYP51A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096186-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-08-30 | — | — | WO | disclosed |