Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MC5R | P33032 | 1/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12737691 | 0.88 | MC4R (0.44) | MC4RKMT2ASCN9ACYP51A1PABPC1 | |
| SCHEMBL14435248 | 0.84 | ADAM17 (0.43) | MC4RADAM17ADAMTS5MC5RMC3R | |
| SCHEMBL14435238 | 0.84 | ADAM17 (0.43) | MC4RADAM17ADAMTS5MC5RMC3R | |
| SCHEMBL12713171 | 0.82 | CALCA (0.46) | MC4RADAM17ADAMTS5MC5RMC3R | |
| SCHEMBL12713160 | 0.80 | ADAM17 (0.44) | KMT2AADAM17ADAMTS5 | |
| SCHEMBL12713317 | 0.80 | CALCA (0.42) | MC4RADAM17ADAMTS5CYP51A1MC5R | |
| SCHEMBL12738196 | 0.80 | MC4R (0.52) | MC4RKMT2AMAPK1MC5RMC3R | |
| SCHEMBL12737362 | 0.80 | MC4R (0.45) | MC4RKMT2APABPC1MAPK1 | |
| SCHEMBL14431445 | 0.79 | MC4R (0.51) | MC4RMC3R | |
| SCHEMBL12713318 | 0.78 | CALCA (0.41) | MC4RADAM17ADAMTS5CYP51A1MC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096186-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-08-30 | — | — | WO | disclosed |