Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.40 |
| ▸ | CYP51A1 | Q16850 | 3/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | CALCA | P06881 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | UGCG | Q16739 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14436001 | 1.00 | CCR1 (0.42) | CCR1PROKR1CYP51A1ADAM17ADAMTS5 | |
| SCHEMBL14435995 | 0.87 | ADAM17 (0.41) | CCR1PROKR1ADAM17ADAMTS5TACR1 | |
| SCHEMBL14435999 | 0.87 | ADAM17 (0.41) | CCR1PROKR1ADAM17ADAMTS5TACR1 | |
| SCHEMBL14435998 | 0.86 | CCR1 (0.42) | CCR1PROKR1CYP51A1ADAM17ADAMTS5 | |
| SCHEMBL14435262 | 0.84 | HRH2 (0.43) | CCR1PROKR1CYP51A1ADAM17ADAMTS5 | |
| SCHEMBL14436005 | 0.82 | CCR1 (0.42) | CCR1PROKR1CYP51A1ADAM17ADAMTS5 | |
| SCHEMBL14435994 | 0.82 | CCR1 (0.42) | CCR1PROKR1CYP51A1ADAM17ADAMTS5 | |
| SCHEMBL14436003 | 0.80 | CCR1 (0.43) | CCR1CYP51A1ADAM17ADAMTS5ALDH1A1 | |
| SCHEMBL14435997 | 0.80 | CCR1 (0.43) | CCR1CYP51A1ADAM17ADAMTS5ALDH1A1 | |
| SCHEMBL13941525 | 0.79 | TP53 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096186-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-08-30 | — | — | WO | disclosed |