Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.43 |
| ▸ | CYP51A1 | Q16850 | 4/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | UGCG | Q16739 | 3/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | PYGM | P11217 | 1/20 | 0.37 |
| ▸ | CALCA | P06881 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435997 | 1.00 | CCR1 (0.43) | CCR1CYP51A1ADAM17ADAMTS5ALDH1A1 | |
| SCHEMBL12713182 | 0.90 | CALCA (0.46) | CCR1CYP51A1ALDH1A1CYP3A4UGCG | |
| SCHEMBL14436005 | 0.88 | CCR1 (0.42) | CCR1CYP51A1ADAM17ADAMTS5ALDH1A1 | |
| SCHEMBL14435994 | 0.88 | CCR1 (0.42) | CCR1CYP51A1ADAM17ADAMTS5ALDH1A1 | |
| SCHEMBL14435628 | 0.88 | KMT2A (0.46) | CCR1CYP51A1ALDH1A1CYP3A4UGCG | |
| SCHEMBL14435596 | 0.88 | AKT1 (0.43) | ADAM17ADAMTS5 | |
| SCHEMBL14436006 | 0.88 | ADAM17 (0.43) | CCR1CYP51A1ADAM17ADAMTS5ALDH1A1 | |
| SCHEMBL14436008 | 0.88 | ADAM17 (0.43) | CCR1CYP51A1ADAM17ADAMTS5ALDH1A1 | |
| SCHEMBL14435998 | 0.84 | CCR1 (0.42) | CCR1CYP51A1ADAM17ADAMTS5ALDH1A1 | |
| SCHEMBL14435607 | 0.80 | CCR1 (0.42) | CCR1CYP51A1ADAM17ADAMTS5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096186-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-08-30 | — | — | WO | disclosed |