Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23607029 | 0.79 | KISS1R (0.33) | ALDH1A1 | |
| SCHEMBL14435659 | 0.75 | TRPV1 (0.44) | ALDH1A1PLA2G2CTRPV1HDAC7HDAC8 | |
| SCHEMBL12435058 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TRPV1TSHRNFKB1KDM4E | |
| SCHEMBL12435038 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TRPV1TSHRNFKB1KDM4E | |
| SCHEMBL12435051 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TRPV1TSHRNFKB1KDM4E | |
| SCHEMBL12435037 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TRPV1TSHRNFKB1KDM4E | |
| SCHEMBL12435048 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TRPV1TSHRNFKB1KDM4E | |
| SCHEMBL12435104 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TRPV1TSHRNFKB1KDM4E | |
| SCHEMBL12435099 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TRPV1TSHRNFKB1KDM4E | |
| SCHEMBL12435056 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TRPV1TSHRNFKB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339851-A1 | CXCR6 SULFONAMIDE COMPOUNDS | CHEMOCENTRYX, INC. | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339851-A1 | CXCR6 SULFONAMIDE COMPOUNDS | CXCR6, CXCR1, CXCR2 | ALDH1A1 1964/4885PLA2G2C 3187/4885TRPV1 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.