Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12437594 | 0.90 | LMNA (0.51) | ALDH1A1LMNAPKMSLC5A7HRH3 | |
| SCHEMBL12437731 | 0.86 | HRH3 (0.55) | ALDH1A1LMNAPKMSLC5A7HRH3 | |
| SCHEMBL12437532 | 0.85 | HRH3 (0.69) | ALDH1A1LMNASLC5A7HRH3KMT2A | |
| SCHEMBL12437525 | 0.85 | HRH3 (0.69) | ALDH1A1LMNASLC5A7HRH3KMT2A | |
| SCHEMBL12437340 | 0.84 | HRH3 (0.68) | ALDH1A1LMNAPKMSLC5A7HRH3 | |
| SCHEMBL12437596 | 0.83 | HRH3 (0.61) | ALDH1A1LMNAHRH3KMT2AMEN1 | |
| SCHEMBL12437341 | 0.82 | OPRM1 (0.61) | ALDH1A1LMNAHRH3KMT2AMEN1 | |
| SCHEMBL12437334 | 0.82 | OPRM1 (0.61) | ALDH1A1LMNAHRH3KMT2AMEN1 | |
| SCHEMBL12437610 | 0.80 | KMT2A (0.53) | SLC5A7HRH3ROCK2ROCK1KMT2A | |
| SCHEMBL12437762 | 0.79 | HRH3 (0.52) | ALDH1A1LMNAPKMSLC5A7HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007098086-A2 | HYDROXYPIPERIDINE DERIVATIVES AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2007-08-30 | — | — | WO | disclosed |