Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12737875 | 0.88 | HTR6 (0.38) | HTR6SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL12737970 | 0.87 | SLC6A2 (0.40) | HTR6SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL13941325 | 0.74 | HTR6 (0.40) | HTR6SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL13002978 | 0.73 | CALCA (0.45) | — | |
| SCHEMBL12713217 | 0.68 | CNR1 (0.42) | POLB | |
| SCHEMBL13003120 | 0.68 | HTR6 (0.40) | HTR6SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL12737348 | 0.67 | KCNH2 (0.41) | HTR6SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL13941152 | 0.66 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL12713199 | 0.66 | SMN1; SMN2 (0.45) | POLB | |
| SCHEMBL12738170 | 0.66 | HRH3 (0.41) | HTR6SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096186-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-08-30 | — | — | WO | disclosed |