Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12746494 | 0.90 | CYP3A4 (0.32) | LMNAL3MBTL1ALDH1A1TSHR | |
| SCHEMBL14521931 | 0.81 | ALDH1A1 (0.39) | LMNAL3MBTL1POLBHCAR2ALDH1A1 | |
| SCHEMBL12746484 | 0.78 | ALDH1A1 (0.36) | LMNAPOLBHCAR2ALDH1A1TSHR | |
| SCHEMBL10009516 | 0.76 | ALDH1A1 (0.40) | LMNAL3MBTL1POLBHCAR2ALDH1A1 | |
| SCHEMBL12921953 | 0.75 | CYP2D6 (0.35) | HCAR2ALDH1A1TSHR | |
| SCHEMBL18501609 | 0.74 | PGK1 (0.35) | — | |
| SCHEMBL10010823 | 0.74 | ALDH1A1 (0.39) | LMNAL3MBTL1POLBALDH1A1TSHR | |
| SCHEMBL12921952 | 0.72 | CYP2D6 (0.39) | LMNAL3MBTL1POLBALDH1A1TSHR | |
| SCHEMBL10010011 | 0.71 | ACHE (0.41) | POLBALDH1A1TSHR | |
| SCHEMBL10012569 | 0.71 | TSHR (0.30) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |