Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345211 | 0.90 | TBXA2R (0.40) | MEN1KMT2ATDP1P2RX3KCNH2 | |
| SCHEMBL8494049 | 0.89 | PTGDR2 (0.37) | MEN1KMT2APTGDR2P2RX3TBXA2R | |
| Carbamic Acid SCHEMBL667612 | 0.88 | PIM1 (0.36) | MEN1KMT2APTGDR2TDP1P2RX3 | |
| SCHEMBL4680536 | 0.88 | MEN1 (0.38) | MEN1KMT2ATDP1P2RX3RHEB | |
| SCHEMBL5852651 | 0.87 | KCNH2 (0.35) | MEN1KMT2ATDP1PIM1PIM3 | |
| Carbamic Acid SCHEMBL5064953 | 0.86 | PIM1 (0.35) | MEN1KMT2ATDP1P2RX3RHEB | |
| SCHEMBL14439807 | 0.86 | KCNH2 (0.38) | MEN1KMT2ATDP1KCNH2 | |
| SCHEMBL597334 | 0.86 | P2RX3 (0.33) | MEN1KMT2ATDP1P2RX3PIM1 | |
| SCHEMBL7079061 | 0.86 | L3MBTL1 (0.35) | MEN1KMT2ATDP1P2RX3PIM1 | |
| SCHEMBL28687873 | 0.85 | MEN1 (0.40) | MEN1KMT2ATDP1P2RX3RHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |