Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967782 | 0.92 | LMNA (0.39) | TBXA2RLMNARXFP1MEN1KMT2A | |
| SCHEMBL14439810 | 0.90 | MEN1 (0.37) | TBXA2RMEN1KMT2ATDP1KCNH2 | |
| SCHEMBL6969096 | 0.90 | LMNA (0.42) | TBXA2RLMNARXFP1ENPP2TBXAS1 | |
| SCHEMBL6968985 | 0.90 | KDM4E (0.38) | ENPP2KDM4EP2RX3 | |
| SCHEMBL8343038 | 0.89 | TBXA2R (0.42) | TBXA2RLMNARXFP1MEN1KMT2A | |
| SCHEMBL8347165 | 0.89 | LMNA (0.45) | TBXA2RLMNARXFP1MEN1KMT2A | |
| Carbamic Acid SCHEMBL5064953 | 0.89 | PIM1 (0.35) | MEN1KMT2AENPP2TDP1KCNH2 | |
| SCHEMBL6969945 | 0.88 | KCNH2 (0.34) | MEN1KMT2AENPP2TDP1KCNH2 | |
| SCHEMBL4680536 | 0.86 | MEN1 (0.38) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| Carbamic Acid SCHEMBL667612 | 0.86 | PIM1 (0.36) | MEN1KMT2ATDP1KCNH2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |