Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.43 |
| ▸ | DRD2 | P14416 | 9/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439855 | 0.85 | TDP1 (0.33) | P2RX3DCTPP1 | |
| SCHEMBL6971451 | 0.84 | HSP90B1 (0.33) | P2RX3TP53 | |
| SCHEMBL6966848 | 0.84 | TDP1 (0.42) | GAATLR7TP53MAPT | |
| SCHEMBL14439868 | 0.83 | DCTPP1 (0.34) | P2RX3DCTPP1 | |
| SCHEMBL5852651 | 0.83 | KCNH2 (0.35) | — | |
| Hydrochloric Acid SCHEMBL6973616 | 0.81 | CCR9 (0.37) | DRD2TBXA2RLMNATP53 | |
| SCHEMBL14002294 | 0.80 | CCR9 (0.32) | — | |
| Hydrochloric Acid SCHEMBL6962246 | 0.79 | TDP1 (0.31) | — | |
| SCHEMBL6970372 | 0.79 | CCR2 (0.43) | LMNAMAPT | |
| SCHEMBL6970704 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |