Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971451 | 0.90 | HSP90B1 (0.33) | TDP1P2RX3 | |
| SCHEMBL6966848 | 0.90 | TDP1 (0.42) | TDP1 | |
| SCHEMBL5852651 | 0.89 | KCNH2 (0.35) | TDP1 | |
| SCHEMBL14002294 | 0.89 | CCR9 (0.32) | TDP1 | |
| SCHEMBL14439868 | 0.87 | DCTPP1 (0.34) | TDP1P2RX3DCTPP1 | |
| Hydrochloric Acid SCHEMBL6973616 | 0.87 | CCR9 (0.37) | TDP1 | |
| SCHEMBL6972194 | 0.86 | NPC1 (0.41) | P2RX3 | |
| SCHEMBL6961345 | 0.86 | L3MBTL1 (0.39) | P2RX3 | |
| Hydrochloric Acid SCHEMBL6962246 | 0.85 | TDP1 (0.31) | TDP1 | |
| SCHEMBL14001658 | 0.85 | P2RX3 (0.35) | TDP1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |