Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.57 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.55 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL813148 | 1.00 | RAB9A (0.61) | RAB9AUSP2CYP19A1KCNN4KCNE1 | |
| Hydrochloric Acid SCHEMBL19583319 | 0.93 | USP2 (0.55) | RAB9AUSP2CYP19A1KCNN4KCNE1 | |
| SCHEMBL12833774 | 0.89 | RAB9A (0.73) | RAB9AUSP2CYP19A1KCNN4SMN1; SMN2 | |
| SCHEMBL7442397 | 0.88 | USP2 (0.85) | RAB9AUSP2CYP19A1KCNN4CYP3A4 | |
| SCHEMBL9050608 | 0.87 | CYP19A1 (0.54) | RAB9AUSP2CYP19A1KCNN4ALDH1A1 | |
| SCHEMBL10631898 | 0.84 | CYP19A1 (0.86) | RAB9AUSP2CYP19A1CYP3A4 | |
| Triphenylmethanol SCHEMBL456603 | 0.84 | CYP19A1 (0.50) | CYP19A1KCNN4ALDH1A1KMT2ACYP3A4 | |
| Triphenylmethanol SCHEMBL1332873 | 0.84 | CYP19A1 (0.50) | CYP19A1KCNN4ALDH1A1KMT2ACYP3A4 | |
| Triphenylmethanol SCHEMBL700 | 0.84 | CYP19A1 (0.50) | CYP19A1KCNN4ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL30293723 | 0.83 | KCNN4 (0.58) | RAB9AUSP2CYP19A1KCNN4KCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12286389-B2 | Crystalline form a of 2, 2-bis(4-fluorophenyl)-2-phenylacetamide and preparation method therefor and application thereof | Shenzhen Jingtai Technology Co., Ltd (CN) | 2025-04-29 | — | — | US | disclosed |
| US-20220033347-A1 | CRYSTALLINE FORM A OF 2, 2-BIS(4-FLUOROPHENYL)-2-PHENYLACETAMIDE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shenzhen Jingtai Technology Co., Ltd (CN) | 2022-02-03 | — | — | US | disclosed |
| WO-2011034860-A1 | TREATMENT METHODS USING TRIARYL METHANE COMPOUNDS | ICAGEN, INC. (US) | 2011-03-24 | — | — | WO | disclosed |
| US-20100056637-A1 | TREATMENT METHODS USING TRIARYL METHANE COMPOUNDS | ICAGEN, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| US-20090036538-A1 | TREATMENT METHODS USING TRIARYL METHANE COMPOUNDS | ICAGEN, INC. (US) | 2009-02-05 | — | — | US | disclosed |
| EP-1968563-A2 | TREATMENT METHODS USING TRIARYL METHANE COMPOUNDS | Icagen, Inc. (US) | 2008-09-17 | — | — | EP | disclosed |
| EP-1158971-B1 | GARDOS CHANNEL ANTAGONISTS | ICAGEN INC (US) | 2007-08-22 | — | — | EP | disclosed |
| US-20070185209-A1 | Treatment methods using triaryl methane compounds | ICAGEN, INC. (US) | 2007-08-09 | — | — | US | disclosed |
| WO-2007075849-A2 | TREATMENT METHODS USING TRIARYL METHANE COMPOUNDS | ICAGEN, INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| EP-1158971-A4 | GARDOS CHANNEL ANTAGONISTS | ICAGEN INC (US) | 2003-04-16 | — | — | EP | disclosed |
| EP-1158971-A1 | GARDOS CHANNEL ANTAGONISTS | Icagen, Inc. (US) | 2001-12-05 | — | — | EP | disclosed |
| US-6288122-B1 | A TRIPHENYL ACETAMIDE | ICAGEN, INC. | 2001-09-11 | — | — | US | disclosed |
| WO-2000050026-A1 | GARDOS CHANNEL ANTAGONISTS | ICAGEN, INC. (US) | 2000-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185209-A1 | Treatment methods using triaryl methane compounds | KCNH3, KCNH2, KCNJ2 | RAB9A 4151/4885USP2 2951/4885CYP19A1 2583/4885 |
| US-20090036538-A1 | TREATMENT METHODS USING TRIARYL METHANE COMPOUNDS | KCNH3, KCNH2, KCNJ2 | RAB9A 4151/4885USP2 2951/4885CYP19A1 2583/4885 |
| US-12286389-B2 | Crystalline form a of 2, 2-bis(4-fluorophenyl)-2-phenylacetamide and preparation method therefor and application thereof | WEE2, WEE1, WASF2 | RAB9A 3017/4885USP2 1535/4885CYP19A1 488/4885 |
| US-20220033347-A1 | CRYSTALLINE FORM A OF 2, 2-BIS(4-FLUOROPHENYL)-2-PHENYLACETAMIDE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | WEE2, WEE1, WASF2 | RAB9A 3017/4885USP2 1535/4885CYP19A1 488/4885 |
| US-20100056637-A1 | TREATMENT METHODS USING TRIARYL METHANE COMPOUNDS | LTC4S, LTB4R2, CYSLTR2 | RAB9A 3445/4885USP2 1539/4885CYP19A1 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.