SCHEMBL14439890

SCHEMBL14439890

CP(=O)(CCN)Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
SRC P12931 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
HPGD P15428 2/20 0.44
ALDH1A1 P00352 1/20 0.43
ANPEP P15144 2/20 0.42
LAP3 P28838 2/20 0.42
PKM P14618 1/20 0.42
TAAR1 Q96RJ0 1/20 0.41
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14600653 0.89 L3MBTL1 (0.43) L3MBTL1SRCTDP1HPGDANPEP
SCHEMBL5491492 0.82 L3MBTL1 (0.52) L3MBTL1SRCTDP1HPGDANPEP
SCHEMBL4159188 0.80 KLK8 (0.50) L3MBTL1SRCTDP1ALDH1A1ANPEP
Ethylenediamine SCHEMBL10787896 0.80 PKM (0.53) L3MBTL1SRCTDP1HPGDANPEP
SCHEMBL5490967 0.79 L3MBTL1 (0.49) L3MBTL1SRCTDP1
SCHEMBL27749607 0.78 SRC (0.47) L3MBTL1SRCTDP1ALDH1A1ANPEP
SCHEMBL3628765 0.78 AOX1 (0.49) L3MBTL1SRCTDP1HPGDANPEP
SCHEMBL5483772 0.78 L3MBTL1 (0.55) L3MBTL1SRCTDP1HPGDANPEP
Triphenyl Phosphate SCHEMBL28207717 0.75 TAAR1 (0.52) L3MBTL1SRCTDP1ANPEPLAP3
SCHEMBL5945294 0.74 ANPEP (0.44) L3MBTL1SRCALDH1A1ANPEPLAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070190523-A1 Method and compositions for identifying anti-hiv therapeutic compounds GILEAD SCIENCES, INC. 2007-08-16 US disclosed