Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 11/20 | 0.39 |
| ▸ | PRKCA | P17252 | 11/20 | 0.39 |
| ▸ | PRKCG | P05129 | 10/20 | 0.39 |
| ▸ | PRKCB | P05771 | 10/20 | 0.39 |
| ▸ | PRKCH | P24723 | 9/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 9/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 9/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 7/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 7/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 7/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 6/20 | 0.39 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14440356 | 0.93 | GSK3B (0.39) | CAMK2DPRKCAPRKCGPRKCBPRKCH | |
| SCHEMBL14440380 | 0.92 | CAMK2D (0.40) | CAMK2DPRKCAPRKCGPRKCBPRKCH | |
| SCHEMBL14440454 | 0.92 | CAMK2D (0.40) | CAMK2DPRKCAPRKCGPRKCBPRKCH | |
| SCHEMBL14440368 | 0.91 | PRKD1 (0.38) | CAMK2DPRKCACAMK2BCAMK2GCAMK2A | |
| SCHEMBL14440423 | 0.76 | CAMK2D (0.44) | CAMK2DPRKCAPRKCGPRKCBPRKCH | |
| SCHEMBL14440422 | 0.76 | CAMK2D (0.44) | CAMK2DPRKCAPRKCGPRKCBPRKCH | |
| SCHEMBL14440426 | 0.76 | CAMK2D (0.44) | CAMK2DPRKCAPRKCGPRKCBPRKCH | |
| SCHEMBL8354266 | 0.75 | CAMK2D (0.44) | CAMK2DPRKCAPRKCGPRKCBPRKCH | |
| SCHEMBL8355324 | 0.75 | GSK3B (0.38) | CAMK2DPRKCAPRKCGPRKCBPRKCH | |
| SCHEMBL14440395 | 0.72 | PRKCB (0.42) | CAMK2DPRKCAPRKCGPRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262215-B2 | N-carbacycle monosubstituted indolocarbazoles as protein kinase inhibitors | NAD AG (DE) | 2007-08-28 | — | — | US | disclosed |