Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PNLIP | P16233 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | KDM6A | O15550 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 3/20 | 0.35 |
| ▸ | KLK1 | P06870 | 3/20 | 0.35 |
| ▸ | KLK6 | Q92876 | 3/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5387068 | 0.93 | LMNA (0.39) | KLKB1SCN9ACAMK1DTSHRSMN1; SMN2 | |
| SCHEMBL5381063 | 0.92 | KLKB1 (0.44) | KLKB1SCN9ATSHRSMN1; SMN2PNLIP | |
| SCHEMBL5383376 | 0.91 | CA12 (0.42) | SCN9ASNCACA12CA1CA2 | |
| SCHEMBL5386628 | 0.90 | PLAU (0.40) | KLKB1SCN9ACAMK1DTSHRSMN1; SMN2 | |
| SCHEMBL5453190 | 0.89 | CA12 (0.48) | CA12CA1CA2CA9 | |
| SCHEMBL5384012 | 0.89 | KDM1A (0.39) | SCN9ACAMK1DTSHRSMN1; SMN2CA12 | |
| SCHEMBL5392718 | 0.89 | ALOX15 (0.42) | KLKB1CAMK1DSMN1; SMN2CA12CA1 | |
| SCHEMBL5380879 | 0.89 | MEN1 (0.47) | KLKB1SCN9APNLIP | |
| SCHEMBL5396945 | 0.89 | EGLN1 (0.42) | SCN9AEGLN1 | |
| SCHEMBL5388147 | 0.87 | TSHR (0.41) | KLKB1SCN9ATSHRSMN1; SMN2PNLIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197533-A1 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197533-A1 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | DDC, DPP3, AMPD3 | KLKB1 4506/4885SCN9A 4552/4885CAMK1D 4720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.