SCHEMBL14440639

SCHEMBL14440639

OC[C@H]1O[C@@H](n2ccc3c(Cl)ncnc32)[C@H](O)C[C@@H](O)[C@@H]1O

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 2/20 0.51
▸ METTL3 Q86U44 1/20 0.50
▸ METTL14 Q9HCE5 1/20 0.50
▸ SLC29A1 Q99808 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14568724 0.90 SLC29A1 (0.49) ADKMETTL3METTL14SLC29A1
SCHEMBL14568617 0.90 SLC29A1 (0.49) ADKMETTL3METTL14SLC29A1
SCHEMBL13005628 0.87 ADK (0.64) ADKMETTL3METTL14SLC29A1
SCHEMBL10160817 0.87 ADK (0.64) ADKMETTL3METTL14SLC29A1
SCHEMBL1797344 0.87 ADK (0.64) ADKMETTL3METTL14SLC29A1
SCHEMBL10131093 0.87 ADK (0.64) ADKMETTL3METTL14SLC29A1
SCHEMBL14440645 0.87 ADK (0.64) ADKMETTL3
SCHEMBL14440630 0.86 ADK (0.63) ADKMETTL3METTL14SLC29A1
SCHEMBL14440901 0.86 ADK (0.63) ADKMETTL3METTL14SLC29A1
SCHEMBL23982307 0.85 PRMT5 (0.47) ADKSLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070185063-A1 Seven-membered ring nucleosides IDENIX PHARMACEUTICALS, INC. 2007-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070185063-A1 Seven-membered ring nucleosides NSUN2, NSUN3, HAVCR2 ADK 359/4885METTL3 80/4885METTL14 248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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