Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 2/20 | 0.64 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.62 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.62 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10131093 | 1.00 | ADK (0.64) | ADKMETTL3METTL14SLC29A1 | |
| SCHEMBL1797344 | 1.00 | ADK (0.64) | ADKMETTL3METTL14SLC29A1 | |
| SCHEMBL13005628 | 1.00 | ADK (0.64) | ADKMETTL3METTL14SLC29A1 | |
| SCHEMBL14440901 | 0.99 | ADK (0.63) | ADKMETTL3METTL14SLC29A1 | |
| SCHEMBL14440630 | 0.99 | ADK (0.63) | ADKMETTL3METTL14SLC29A1 | |
| SCHEMBL14429029 | 0.90 | SLC29A1 (0.54) | ADKSLC29A1 | |
| SCHEMBL14429079 | 0.90 | SLC29A1 (0.54) | ADKSLC29A1 | |
| SCHEMBL23544706 | 0.89 | ADK (0.53) | ADKMETTL3METTL14 | |
| SCHEMBL1689454 | 0.89 | METTL3 (0.55) | ADKMETTL3SLC29A1 | |
| SCHEMBL18636459 | 0.89 | ADK (0.53) | ADKMETTL3METTL14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338706-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-11-04 | — | — | US | disclosed |
| WO-2018133835-A1 | NUCLEOSIDE ANALOGUE REGULATING MAMMALIAN CIRCADIAN RHYTHM | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-07-26 | — | — | WO | disclosed |
| WO-2018133854-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-07-26 | — | — | WO | disclosed |
| EP-3133080-A1 | NOVEL CYTOSTATIC 7-DEAZAPURINE NUCLEOSIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2017-02-22 | — | — | EP | disclosed |
| US-8093226-B2 | Cytostatic 7-deazapurine nucleosides | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ASCR, V.V.I. (CZ) | 2012-01-10 | — | — | US | disclosed |
| US-20090203637-A1 | NOVEL CYTOSTATIC 7-DEAZAPURINE NUCLEOSIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ASCR, V.V.I. | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338706-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | PER2, CRY1, ADORA2A | ADK 4/4885METTL3 39/4885METTL14 65/4885 |
| US-20090203637-A1 | NOVEL CYTOSTATIC 7-DEAZAPURINE NUCLEOSIDES | TYMP, TYMS, DPYD | ADK 442/4885METTL3 322/4885METTL14 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.