Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14568792 | 1.00 | THRB (0.37) | THRBLMNACA2CA1CA9 | |
| SCHEMBL23273655 | 0.91 | THRB (0.41) | THRBLMNACA2CA1CA9 | |
| SCHEMBL5930297 | 0.91 | THRB (0.41) | THRBLMNACA2CA1CA9 | |
| SCHEMBL5930290 | 0.91 | THRB (0.41) | THRBLMNACA2CA1CA9 | |
| SCHEMBL9026184 | 0.91 | THRB (0.41) | THRBLMNACA2CA1CA9 | |
| SCHEMBL13318466 | 0.88 | THRB (0.40) | THRBLMNACA2CA1CA9 | |
| SCHEMBL3929478 | 0.84 | CA2 (0.33) | THRBLMNACA2CA1CA9 | |
| SCHEMBL3917523 | 0.84 | CA2 (0.33) | THRBLMNACA2CA1CA9 | |
| SCHEMBL3917735 | 0.84 | CA2 (0.33) | THRBLMNACA2CA1CA9 | |
| SCHEMBL3920065 | 0.84 | CA2 (0.33) | THRBLMNACA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | NSUN2, NSUN3, HAVCR2 | THRB 4696/4885LMNA 1658/4885CA2 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.