Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14440989 | 1.00 | THRB (0.37) | THRBLMNACA2CA1CA9 | |
| SCHEMBL23273655 | 0.91 | THRB (0.41) | THRBLMNACA2CA1CA9 | |
| SCHEMBL5930297 | 0.91 | THRB (0.41) | THRBLMNACA2CA1CA9 | |
| SCHEMBL5930290 | 0.91 | THRB (0.41) | THRBLMNACA2CA1CA9 | |
| SCHEMBL9026184 | 0.91 | THRB (0.41) | THRBLMNACA2CA1CA9 | |
| SCHEMBL13318466 | 0.88 | THRB (0.40) | THRBLMNACA2CA1CA9 | |
| SCHEMBL3929478 | 0.84 | CA2 (0.33) | THRBLMNACA2CA1CA9 | |
| SCHEMBL3917523 | 0.84 | CA2 (0.33) | THRBLMNACA2CA1CA9 | |
| SCHEMBL3917735 | 0.84 | CA2 (0.33) | THRBLMNACA2CA1CA9 | |
| SCHEMBL3920065 | 0.84 | CA2 (0.33) | THRBLMNACA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025043-A2 | SEVEN-MEMBERED RING NUCLEOSIDES | IDENIX PHARMACEUTICALS, INC. (US) | 2007-03-01 | — | — | WO | disclosed |