Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 15/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5476896 | 0.90 | GRIN2B (0.40) | GRIN2BNPY5RVCP | |
| SCHEMBL5480629 | 0.90 | GRIN2B (0.40) | GRIN2BNPY5RVCP | |
| SCHEMBL8292957 | 0.82 | HRH4 (0.42) | VCPCDK2 | |
| SCHEMBL5477983 | 0.80 | GRIN2B (0.40) | GRIN2BVCPBTK | |
| SCHEMBL5478744 | 0.80 | GRIN2B (0.40) | GRIN2BVCPBTK | |
| SCHEMBL8292639 | 0.80 | GRIN2B (0.40) | GRIN2BVCPBTK | |
| SCHEMBL6021793 | 0.79 | GRIN2B (0.41) | GRIN2BVCPCDK2MAPK8MAPK9 | |
| SCHEMBL6021795 | 0.79 | GRIN2B (0.41) | GRIN2BVCPCDK2MAPK8MAPK9 | |
| SCHEMBL8291913 | 0.77 | HRH4 (0.37) | — | |
| SCHEMBL5473023 | 0.77 | MAP3K14 (0.38) | GRIN2BVCPPIM1CDK2MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185104-A1 | Benzoxazole acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185104-A1 | Benzoxazole acetonitriles | PKD1, PC, GPR119 | GRIN2B 2653/4885NPY5R 92/4885VCP 4528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.