Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414744 | 0.92 | ALDH1A1 (0.31) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL14445361 | 0.91 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNAPDE10APTGER4 | |
| SCHEMBL14445364 | 0.90 | MAPK1 (0.33) | ALDH1A1MAPTPTGER4KMT2AMAPK1 | |
| SCHEMBL14445362 | 0.88 | ALDH1A1 (0.33) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL14445308 | 0.88 | ALDH1A1 (0.34) | ALDH1A1MAPTLMNAPDE10APTGER4 | |
| SCHEMBL14445363 | 0.85 | ALDH1A1 (0.36) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL14445191 | 0.85 | ALDH1A1 (0.34) | ALDH1A1MAPTLMNAPTGER4NCF1 | |
| SCHEMBL14445304 | 0.85 | ALDH1A1 (0.37) | ALDH1A1MAPTLMNAPDE10APTGER4 | |
| SCHEMBL14445233 | 0.82 | PTGER4 (0.38) | ALDH1A1MAPTLMNAPDE10APTGER4 | |
| SCHEMBL14445367 | 0.82 | MAPK1 (0.38) | ALDH1A1MAPTLMNAPTGER4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |