Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5416163 | 0.93 | ALDH1A1 (0.35) | ALDH1A1MAPTPTGER4HTR4SYK | |
| SCHEMBL14445193 | 0.85 | CDK1 (0.31) | CDK1 | |
| SCHEMBL14445202 | 0.85 | APP (0.35) | CDK1LMNA | |
| SCHEMBL14445366 | 0.85 | ALDH1A1 (0.37) | ALDH1A1MAPTPTGER4KDM4EHCAR3 | |
| SCHEMBL5425430 | 0.84 | CDK1 (0.32) | CDK1 | |
| SCHEMBL14445361 | 0.82 | ALDH1A1 (0.38) | ALDH1A1MAPTPTGER4KDM4EHCAR3 | |
| SCHEMBL5417295 | 0.81 | APP (0.31) | CDK1 | |
| SCHEMBL14445233 | 0.79 | PTGER4 (0.38) | ALDH1A1MAPTPTGER4KDM4EHCAR3 | |
| SCHEMBL14445308 | 0.79 | ALDH1A1 (0.34) | ALDH1A1MAPTPTGER4KDM4ELMNA | |
| SCHEMBL14445195 | 0.79 | KMO (0.32) | CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |