Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14445356 | 0.92 | MAPK1 (0.36) | MAPK1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL14445362 | 0.82 | ALDH1A1 (0.33) | MAPK1KDM4EMAPTNPSR1ALDH1A1 | |
| SCHEMBL14445366 | 0.82 | ALDH1A1 (0.37) | MAPK1KDM4EMAPTNPSR1ALDH1A1 | |
| SCHEMBL14445310 | 0.82 | JAK2 (0.33) | KDM4EJAK2JAK1JAK3NR3C1 | |
| SCHEMBL14445364 | 0.82 | MAPK1 (0.33) | MAPK1KDM4EMAPTALDH1A1APAF1 | |
| SCHEMBL5414744 | 0.80 | ALDH1A1 (0.31) | MAPK1MAPTALDH1A1EHMT2EHMT1 | |
| SCHEMBL14445195 | 0.80 | KMO (0.32) | — | |
| SCHEMBL14445363 | 0.79 | ALDH1A1 (0.36) | MAPK1KDM4EMAPTNPSR1ALDH1A1 | |
| SCHEMBL14445298 | 0.79 | CNR1 (0.33) | ALDH1A1 | |
| SCHEMBL14445237 | 0.79 | KMO (0.35) | MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |