Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCA | P06881 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067727 | 0.87 | CALCA (0.65) | CALCAKDM4EPIK3C3L3MBTL1TP53 | |
| SCHEMBL4067964 | 0.84 | CALCA (0.69) | CALCAKDM4EPIK3C3L3MBTL1TP53 | |
| SCHEMBL4072599 | 0.83 | CALCA (0.68) | CALCAKDM4EPIK3C3L3MBTL1TP53 | |
| SCHEMBL967973 | 0.81 | CALCA (0.51) | CALCAKDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL7262571 | 0.77 | CALCA (0.53) | CALCAKDM4EL3MBTL1TP53HTT | |
| SCHEMBL7258795 | 0.76 | CALCA (0.69) | CALCAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4066023 | 0.76 | CALCA (0.54) | CALCAKDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL4762076 | 0.74 | CALCA (0.52) | CALCAKDM4EPIK3C3L3MBTL1TP53 | |
| SCHEMBL4067974 | 0.74 | CALCA (0.56) | CALCAKDM4EL3MBTL1TP53HTT | |
| SCHEMBL4769028 | 0.73 | CALCA (0.74) | CALCAKDM4EL3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185007-A1 | Aza-quinolinol phosphonate integrase inhibitor compounds | JIN HAOLUN | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185007-A1 | Aza-quinolinol phosphonate integrase inhibitor compounds | CDKL5, CDKL1, CDKL3 | CALCA 4813/4885KDM4E 303/4885PIK3C3 1112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.