Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.53 |
| ▸ | CA2 | P00918 | 8/20 | 0.53 |
| ▸ | CA4 | P22748 | 8/20 | 0.53 |
| ▸ | CA6 | P23280 | 8/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526530 | 0.72 | CCNB2 (0.63) | CA1CA2CA4CA6EIF2AK1 | |
| SCHEMBL23833551 | 0.69 | GABRP (0.46) | CA1CA2CA4CA6CDK1 | |
| SCHEMBL2298597 | 0.69 | CA1 (1.00) | CA1CA2CA4CA6CDK5 | |
| SCHEMBL29370925 | 0.69 | CA1 (1.00) | CA1CA2CA4CA6CDK5 | |
| SCHEMBL29834173 | 0.68 | CA1 (0.47) | CA1CA2CA4CA6KDR | |
| SCHEMBL23649412 | 0.68 | CA1 (0.47) | CA1CA2CA4CA6KDR | |
| SCHEMBL9531089 | 0.68 | CA1 (0.71) | CA1CA2CA4CA6CDK5 | |
| SCHEMBL12382594 | 0.68 | CA1 (0.69) | CA1CA2CA4CA6CDK5 | |
| SCHEMBL4627835 | 0.68 | CA1 (0.69) | CA1CA2CA4CA6CDK5 | |
| SCHEMBL9527328 | 0.67 | CA1 (0.50) | CA1CA2CA4CA6KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173535-A1 | Oxadiazoles having antiproliferative activity | SASSARI, UNIVERSITA' DEGLISTUDI DI (IT) | 2007-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173535-A1 | Oxadiazoles having antiproliferative activity | MKI67, OXA1L, TOP1 | CA1 2771/4885CA2 2162/4885CA4 2819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.