Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.50 |
| ▸ | CA2 | P00918 | 12/20 | 0.50 |
| ▸ | CA4 | P22748 | 12/20 | 0.50 |
| ▸ | CA6 | P23280 | 12/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946827 | 0.82 | CA1 (0.48) | CA1CA2CA4CA6KDR | |
| SCHEMBL9526776 | 0.81 | ADORA3 (0.43) | CA1CA2CA4CA6ADORA3 | |
| SCHEMBL10381644 | 0.81 | CA1 (0.41) | CA1CA2CA4CA6ADORA3 | |
| SCHEMBL9526845 | 0.80 | ADORA3 (0.40) | CA1CA2CA4CA6ADORA3 | |
| SCHEMBL9530865 | 0.78 | CA1 (0.50) | CA1CA2CA4CA6CDK1 | |
| SCHEMBL9528210 | 0.74 | CA1 (0.46) | CA1CA2CA4CA6CHEK1 | |
| SCHEMBL9528165 | 0.69 | CA1 (0.57) | CA1CA2CA4CA6 | |
| SCHEMBL9528764 | 0.69 | CA1 (0.53) | CA1CA2CA4CA6CDK1 | |
| SCHEMBL4627835 | 0.69 | CA1 (0.69) | CA1CA2CA4CA6CDK1 | |
| SCHEMBL30251048 | 0.69 | CA1 (0.69) | CA1CA2CA4CA6CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| WO-1990015800-A1 | INDENOINDOLE COMPOUNDS | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |