Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ACP1 | P24666 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.41 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | RHOC | P08134 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863428 | 0.81 | TACR1 (0.48) | LMNAALDH1A1ACP1MAPTTACR1 | |
| SCHEMBL6864244 | 0.81 | LMNA (0.45) | LMNAALDH1A1ACP1MAPTTACR1 | |
| SCHEMBL6863055 | 0.80 | CACNA1H (0.52) | LMNAALDH1A1ACP1MAPTTACR1 | |
| SCHEMBL12496289 | 0.79 | KDM4E (0.37) | ALDH1A1MAPTGPR35 | |
| SCHEMBL1445331 | 0.77 | LMNA (0.55) | LMNAALDH1A1ACP1MAPTTACR1 | |
| SCHEMBL13568424 | 0.77 | EPHX2 (0.59) | LMNAALDH1A1ACP1TACR1NAMPT | |
| SCHEMBL4278127 | 0.76 | CXCR3 (0.56) | LMNAALDH1A1ACP1MAPTTACR1 | |
| SCHEMBL6863505 | 0.76 | LMNA (0.50) | LMNAALDH1A1ACP1MAPTTACR1 | |
| SCHEMBL6871047 | 0.75 | ACP1 (0.49) | LMNAALDH1A1ACP1MAPTTACR1 | |
| SCHEMBL4277997 | 0.75 | CXCR3 (0.55) | LMNAALDH1A1ACP1MAPTTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032291-A1 | SELECTIVE CALCIUM CHANNEL MODULATORS | ZALICUS PHARMACEUTICALS LTD . (CA) | 2011-03-24 | — | — | WO | disclosed |